Large genetic screens for gynogenesis and androgenesis haploid inducers in Arabidopsis thaliana failed to identify mutants

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Large genetic screens for gynogenesis and androgenesis haploid inducers in Arabidopsis thaliana failed to identify mutants

Gynogenesis is a process in which the embryo genome originates exclusively from female origin, following embryogenesis stimulation by a male gamete. In contrast, androgenesis is the development of embryos that contain only the male nuclear genetic background. Both phenomena are of great interest in plant breeding as haploidization is an efficient tool to reduce the length of breeding schemes to...

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How to make haploid Arabidopsis thaliana

The haploid inducer is a cenh3-1 null mutant in the Col-0 ecotype that is complemented by a CENH3 transgene called GFP-tailswap (cenh3-1 is embryo lethal). It has a vegetative phenotype that varies in intensity depending on growth conditions. Rosette leaves are slightly curled, and it also has shorter internodes after bolting. The mutant is mostly male sterile, but has reasonable female fertili...

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A haploid genetics toolbox for Arabidopsis thaliana.

Genetic analysis in haploids provides unconventional yet powerful advantages not available in diploid organisms. In Arabidopsis thaliana, haploids can be generated through seeds by crossing a wild-type strain to a transgenic strain with altered centromeres. Here we report the development of an improved haploid inducer (HI) strain, SeedGFP-HI, that aids selection of haploid seeds prior to germin...

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Genetic analysis of salt-tolerant mutants in Arabidopsis thaliana.

Stress caused by the increased salinity of irrigated fields impairs plant growth and is one of the major constraints that limits crop productivity in many important agricultural areas. As a contribution to solving such agronomic problems, we have carried out a large-scale screening for Arabidopsis thaliana mutants induced on different genetic backgrounds by EMS treatment, fast neutron bombardme...

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Haploid genetic screens in human cells identify host factors used by pathogens.

Loss-of-function genetic screens in model organisms have elucidated numerous biological processes, but the diploid genome of mammalian cells has precluded large-scale gene disruption. We used insertional mutagenesis to develop a screening method to generate null alleles in a human cell line haploid for all chromosomes except chromosome 8. Using this approach, we identified host factors essentia...

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ژورنال

عنوان ژورنال: Frontiers in Plant Science

سال: 2015

ISSN: 1664-462X

DOI: 10.3389/fpls.2015.00147